Showing posts with label corona virus. Show all posts
Showing posts with label corona virus. Show all posts

Friday, 10 April 2020

Ito ang Apat na Gamot Laban COVID-19 na Tinetesting ng WHO



Tenetest ng WHO ang apat na mga gamot na ito na posibleng makatulong laban sa Corona Virus o COVID19. Kasama ang Pilipinas sa team ng Solidarity na nag-aaral at tutuklas kung alin sa mga gamot na ito ang mabisang magpapagaling ng mga apektado ng pandemic na ito.

WHO announced that it would be conducting the trial, called SOLIDARITY, to see if the experimental drugs can curb the coronavirus pandemic. Isa na ang Pilipinas sa mga bansang nakiki-isa sa isinasagawang solidity trial ng World Health Organization (WHO) na may layuning makatuklas ng lunas laban sa coronavirus disease.


WHO is focusing on what it says are the four most promising therapies: an experimental antiviral compound called remdesivir; the malaria medications chloroquine and hydroxychloroquine; a combination of two HIV drugs, lopinavir, and ritonavir; and that same combination plus interferon-beta, an immune system messenger that can help cripple viruses. Some data on their use in COVID-19 patients have already emerged—the HIV combo failed in a small study in China—but WHO believes a large trial with a greater variety of patients is warranted.
Remdesivir
The new coronavirus is giving this compound a second chance to shine. Originally developed by Gilead Sciences to combat Ebola and related viruses, remdesivir shuts down viral replication by inhibiting a key viral enzyme, the RNA-dependent RNA polymerase.
Researchers tested remdesivir last year during the Ebola outbreak in the Democratic Republic of the Congo, along with three other treatments. It did not show any effect. (Two others did.) But the enzyme it targets is similar in other viruses, and in 2017 researchers at the University of North Carolina, Chapel Hill, showed in test tube and animal studies that the drug can inhibit the coronaviruses that cause SARS and MERS.

The first COVID-19 patient diagnosed in the United States—a young man in Snohomish county in Washington—was given remdesivir when his condition worsened; he improved the next day, according to a case report in The New England Journal of Medicine (NEJM). A Californian patient who received remdesivir—and who doctors thought might not survive—recovered as well.

Chloroquine and Hydroxychloroquine
At a press conference, President Donald Trump called chloroquine and hydroxychloroquine a “game changer.” “I feel good about it,” Trump said. His remarks have led to a rush in demand for the decades-old antimalarials. Researchers in France have published a study in which they treated 20 COVID-19 patients with hydroxychloroquine. They concluded that the drug significantly reduced viral load in nasal swabs.

Ritonavir/Lopinavir
This combination drug, sold under the brand name Kaletra, was approved in the United States in 2000 to treat HIV infections. Abbott Laboratories developed lopinavir specifically to inhibit the protease of HIV, an important enzyme that cleaves a long protein chain into peptides during the assembly of new viruses. Because lopinavir is quickly broken down in the human body by our own proteases, it is given with low levels of ritonavir, another protease inhibitor, that lets lopinavir persist longer.

Source: Science Mag

Thursday, 9 April 2020

Dahon ng Saluyot para sa Coronavirus


KUWAIT CITY, April 6: In the midst of research for an effective treatment for the emerging coronavirus, a consultant for Internal Medicine and the Digestive System at the Thunyan Al-Ghanem Center at the Amiri Hospital, Dr Fahd Al-Najjar, confirmed that scientific studies have proven that molokhia leaves whose scientific name (corchorus olitorius) contain flavonoid that helps zinc to enter into the virus-infected cell and prevents the reproduction mechanism of its RNA genetic material to stop the virus from reproducing inside the body, reports Al-Rai daily.

In a statement to Al-Rai, Dr Najjar said, in response to a question raised about a popular Egyptian meal called “Shilo” and its most prominent molokhia ingredients that “the flavonoid substance contained in molokhia, and other agricultural products such as parsley, coriander, dill and cranberries with a high concentration in growing capers buckwheat tea, helps zinc enter the virus-infected cell.

He added flavonoid, according to what is seen in scientific research, is used by the element zinc to enter the inside of the viral cell and these keys are called zinc Ionophore, which is the same way in which the antimalaria drugs, chloroquine and hydroxychloroquine have proven successful against the virus which finally worked.

He pointed out that “one of the well-known zinc properties is quercetin, which is marketed as an antioxidant food supplement because it contains flavonoids, and therefore the compounds or elements present in the components of the so-called cholulu may be effective against the coronavirus, but not because it contains a substance that protects the stomach wall from garlic and lemon, but because studies have shown that molokhia contains the substance flavonoid that helps the element zinc to enter the virus-infected cell and interfere with the mechanism of production of its genetic material RNA and stops reproduction of the virus inside the body.

Source : Arab Times Online

Saturday, 28 March 2020

Coronavirus Symptoms and Risk


There is a spread of a novel coronavirus which is releasing destruction on the city of Wuhan arranged in the Hubei zone of China. The scene of the disease began directly off the bat in December of 2019 and has continued spreading. The people who were the underlying ones to become corrupted were totally associated toward the South China Seafood Wholesale Market which has been closed starting there ahead.

A considerable number cases have been represented by the prosperity experts in China. There are also cases that have been recognized in various countries, by and large spread by the people leaving China, including Chinese people or the people returning from China to their different countries. The disease can spread beginning with one individual then onto the following through contact or even just being in the closeness of the polluted person.

In excess of 20 countries have uncovered cases, including Singapore, Japan, Hong Kong, Thailand, Malaysia, South Korea, Taiwan, Germany, Vietnam, Australia, France, the United States, India, the UK, etc and various countries have set up screening places for the people starting from China.

This is a tremendous gathering of contaminations that are with everything taken into account known as the coronavirus. A huge segment of the known coronavirus signs just effectsly influence the people, for instance, giving them a delicate respiratory disease like the fundamental cold, yet there have been two such occasions of the coronavirus that have exhibited immense ramifications for the spoiled which are Severe Acute Respiratory Syndrome (SARS) coronavirus and Middle East Respiratory Syndrome (MERS) coronavirus.

Reactions: 

Fever, hacking, and inconvenience breathing are a bit of the signs and reactions which have been found in the people corrupted. A part of the patients have similarly reported having a bothered throat. There's been some hypothesis about the genuine sickness causing capacity of the novel coronavirus notwithstanding the way that these cases are not reinforced with authentic proof. People with unremitting ailments and developed patients may introduce increasingly imperative chances of having an outrageous disease as a result of this contamination.

Risk 

The people who are living or circumventing the zone where the disease is basic are at a high threat of pollution according to the WHO. At this moment, the disease is simply present in China and the sum of the non-inhabitants of China who have been debased have wandered out to China starting late and have been in contact with the polluted people who are from China.

Thusly, as showed by WHO, the peril to the people who are not living in China is astoundingly low as long as you don't come into contact with one of the non-occupant Chinese people who are sullied. Similarly, the WHO communicates that fundamental disinfectants can without a lot of a stretch dispose of the contamination in case it is accessible on a surface and besides the continuance time of the disease on any surface is very low.

Conclusion: 

This article shares the sum of the signs to pay uncommon brain to in case you feel that you might be impacted by the contamination, yet in the event that you're a non-inhabitant and have not been in contact with anyone going from China, you get no chance of catching the disease.